Description
This is a case presentation highlighting a case of a myeloproliferative neoplasm that has transformed to AML. The take home points of the presentation are to understand which genetic testing may be important for diagnosis and prognosis of these cases.
Objectives
- List MPN subtypes
- Describe driver mutations in MPNs
- List prognostic factors in AML with preceding MPN
- Understand role of p53 in MPN transformation