Home Events Dealing with the Daily Challenges of the Endometrial Biopsy

Dealing with the Daily Challenges of the Endometrial Biopsy


September 14 2007


1:00 pm - 2:30 pm


  • Dr Anjelica Hodgson
    Dr Anjelica Hodgson

    Dr. Hodgson is a gynecologic pathologist at University Health Network – Toronto General Hospital and she did her pathology training at University of Toronto and Memorial Sloan Kettering Cancer Center. She is an Assistant Professor in the University of Toronto’s Department of Laboratory Medicine and Pathobiology.

  • Dr Blaise Clarke
    Dr Blaise Clarke
  • Dr Marjan Rouzbahman
    Dr Marjan Rouzbahman

    Dr Marjan Rouzbahman is a consultant pathologist at Toronto General Hospital and Associate Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. Since 2008, she has been practicing in diagnostic gynecologic pathology as well as teaching and supervising undergraduate students, medical students, pathology residents and fellows. She is interested in the implementation of molecular testing for diagnostic and targeted therapeutic purposes as part of personalized medicine. She has authored several peer-reviewed articles in gynecologic pathology and textbook chapters including a chapter for the 2020 WHO blue book of gynecologic tumors.


Endometrial biopsies are common specimens seen in all types of pathology practice settings (private, community and academic) and they often present a number of challenges to interpreting pathologists because of a diversity of possible pathologies (both neoplastic and non-neoplastic) and small specimen/sampling size. Over- and under-interpretation are therefore not infrequent and this course aims to arm working pathologists with an updated diagnostic acumen that allows for handling any challenges an endometrial biopsy specimen may provide. The delivery of the course will be divided into the following common “scenarios”: – The biopsy with a proliferative glandular or mucinous/papillary proliferation – The biopsy with hormonal effect – The scant biopsy – The biopsy with evident cancer (with a discussion of biomarkers) Numerous examples and cases from each scenario will presented and discussed, in an effort to cover a) differential diagnoses, b) appropriate terminology and sign out examples, c) clinical and radiological correlation, d) “high stakes”/”can’t miss” entities and e) subsequent clinical management.


  • Describe the general indications for the performance of an endometrial biopsy and how specific diagnoses alter patient management.
  • Apply an approach to deal with a variety of the common challenges presented by non-neoplastic and neoplastic endometrial biopsies.
  • Integrate clinical, radiological and morpho-molecular information (when appropriate) to render the most accurate and useful diagnosis at the time of endometrial biopsy interpretation.


Target Audience

  • Pathologists
  • Residents

CanMEDS Roles

  • Medical Expert (the integrating role)
  • Communicator
  • Collaborator
  • Leader
  • Health Advocate
  • Scholar
  • Professional