Dr. Kovacs is Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, a Consultant Neuropathologist at the Laboratory Medicine Program (LMP) at the University Health Network (UHN) and a Principal Investigator at the Tanz Centre for Research in Neurodegenerative Disease.Dr. Kovacs completed his medical training in Hungary where he specialized in Neurology (1998) and Neuropathology (2003) and obtained a PhD in Neuroscience (2002). From 2007 to 2019, he was an Associate Professor at the Institute of Neurology at the Medical University of Vienna, Austria. He was the leader of the Hungarian (2004-2019) and Austrian (2011-2019) Reference Center for Human Prion Diseases. Dr. Kovacs has also trained at Indiana University (2007) and University of Pennsylvania (2016 and 2017) as a visiting professor/scholar. His major research interest is the neuropathology of neurodegenerative diseases.
1. Understand the classification of neurodegenerative disease.
2. Understand the role of pathology to support the development of in vivo diagnostic and therapy development.
Neurodegenerative diseases are characterised by selective dysfunction and progressive loss of synapses and neurons associated with pathologically altered proteins that deposit primarily in the human brain and spinal cord. Recent discoveries have identified a spectrum of distinct immunohistochemically and biochemically detectable proteins, which serve as a basis for protein-based disease classification. Diagnostic criteria have been updated and disease staging procedures have been proposed. This presentation summarises recent advances in neuropathological diagnosis and reports novel aspects of relevance for general pathological practice.