Home Events CNUP Symposia – Selected Hot Topics in GU Pathology

CNUP Symposia – Selected Hot Topics in GU Pathology


April 19 2021


1:00 pm - 2:30 pm


  • Dr. Michael Bonert
    Dr. Michael Bonert

    Dr. Michael Bonert is a Staff Anatomical Pathologist at St. Joseph’s Healthcare Hamilton and an Assistant Professor at McMaster University. He attended medical school at the University of Toronto, and subsequently trained in Pathology at the University of Toronto. He obtained a FRCPC in Anatomical Pathology and then did subspeciality training in Urologic Pathology at the University of Calgary. Dr. Bonert also has a Bachelor of Applied Science (Mechanical Engineering), and a Master of Applied Science (Mechanical Engineering/Biomedical Engineering) from the University of Toronto. He founded Libre Pathology (https://librepathology.org), an open access web site that delivers pathology information. His interests include urological pathology, gastrointestinal pathology, numerical modelling, data analysis and quality improvement.

  • Dr. Michelle Downes
    Dr. Michelle Downes

    Dr. Downes graduated from the Royal College of Surgeons in Ireland medical school and undertook training in surgery followed by a research fellowship in prostate cancer at University College Dublin. She trained in Anatomic Pathology in Dublin, Ireland and then completed a clinical fellowship in genitourinary pathology at the University Health Network, Toronto. Dr Downes is lead Genitourinary pathologist and Division Head of Anatomic Pathology at Sunnybrook Health Sciences Centre and an Associate Professor in Laboratory Medicine and Pathobiology at the University of Toronto. She is actively engaged in teaching at the undergraduate and postgraduate level. Her research interests are in prognostic and predictive biomarkers of urologic malignancy, particularly in prostate and bladder, with a focus on immune infiltrates and determinants of therapeutic response. She is also engaged in collaborative work examining radiology-pathology correlation and pre-clinical prostate cancer research.

  • Michael Carter
    Michael Carter

    Michael Carter is a Molecular and Anatomical Pathologist at the Nova Scotia Health Authority in Halifax. His clinical practice includes biomarker testing of solid tumors, which increasingly relies on next-generation sequencing to provide diagnostic, prognostic, and predictive information to guide patient management.

    Michael’s research interests focus mainly on genomic profiling of solid tumors and precision medicine.


Overview and update on molecular aspects of bladder cancer presented by Dr. Michelle Downes.

At the end of the session, participants will be able to:

  1. Describe the molecular classification systems for bladder cancer
  2. Appraise the relevance of incorporating molecular features into practice
  3. Recognize potential prognostic and predictive biomarkers


BRCA Mutations In Prostate Cancer: Implications For Targeted Therapy And Screening presented by Dr. Michael Carter.

At the end of the session, participants will be able to:

  1. Identify the benefits of testing metastatic prostate cancer for BRCA1 and BRCA2 mutations.
  2. Describe which patients should be considered for somatic BRCA testing.
  3. List current and emerging testing options for identifying tumors with defects in the BRCA pathway.


Presentation by Dr. Michael Bonert: Observational data in anatomical pathology and quality assessment/quality improvement with an emphasis on urologic pathology.

At the end of the session, participants will be able to:

  1. Understand how observational data can be used in quality assessment and quality improvement
  2. Interpret funnel plots/control charts