Dr Asghar Naqvi
Associate Professor in the Department of Pathology and Molecular Medicine at McMaster University.
I am an Anatomic Pathology consultant with expertise in Pulmonary/Molecular Pathology and Cytopathology.
Dr Peter Sabatini
Dr. Sabatini is a clinical laboratory
geneticist at the University Health Network in Toronto, ON and Assistant Professor in the Department of Laboratory Medicine at the University of Toronto. Dr. Sabatini’s work focuses on improving genomic testing for cancers by translating novel technologies and emerging genomic biomarkers into routine clinical practice.
• Describe the issues in tissue sampling for NSCLC laboratory analyses
• Distinguish the optimal laboratory test choice as applied to different case scenarios
• Interpret the results of molecular and other laboratory tests currently used to assess NSCLC
• Critique current algorithms for NSCLC sample assessment and laboratory testing
• Examine the merits of testing of tumor tissue versus other source material (e.g. ctDNA)
This section will describe the laboratory methods used in the pathological assessment of lung carcinomas. Using case examples, learners will be exposed to molecular data interpretation from various molecular and cytogenetic technologies including next-generation sequencing . Applications of testing tumor and circulating cell-free tumor DNA including the necessary testing algorithms and follow-up recommendations of non-small cell lung cancer will be reviewed. Learners will gain a greater understanding of the advantages and disadvantages of the genomic methodologies used in the laboratory to assess non-small cell lung cancer.